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Analytical Chemist

Connexion Systems + Engineering

Boston, MA

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JOB DETAILS
SALARY
$55–$70 Per Hour
LOCATION
Boston, MA
POSTED
30+ days ago
Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.

Title: Analytical Chemist
Hiring Organization: Connexion Systems & Engineering

Compensation, Benefits, and Employment Type
  • Duration: 1+ year contract
  • Pay rate: $55 - $70/hr (W2)
  • Job Location: Boston, MA (Hybrid – 3 days onsite)
  • Schedule: M-F, 1st shift
  • Job#: bh18555

Description:
We are seeking an experienced Analytical Chemist to support late-stage development activities within a Technical Operations Analytical team. This role will focus on providing analytical support for oligonucleotides, peptides, and peptide-oligonucleotide conjugates, with a strong emphasis on method development, transfer, and validation in a GMP environment.
Key Responsibilities
  • Provide analytical support for oligonucleotide and peptide-oligonucleotide conjugated compounds in late-stage development
  • Independently lead analytical method development, transfer, and validation activities
  • Develop and optimize robust analytical methods including LC/MS, IP-RP HPLC, and SAX HPLC for highly modified oligonucleotide drug substances
  • Perform analysis and purification using techniques such as UPLC, LC-MS, and LC-MS/MS
  • Operate, maintain, and troubleshoot analytical instrumentation
  • Ensure compliance with GLP/GMP standards and documentation requirements
  • Author technical reports, protocols, and validation documentation
  • Collaborate effectively with cross-functional teams while working independently as an analytical subject-matter expert
Qualifications
  • BS or MS in Chemistry or a related scientific discipline
  • 5+ years of commercial, GMP analytical laboratory experience
  • Hands-on experience with oligonucleotide therapeutics is required
  • Strong background in analytical method development and validation
  • Proficiency with mass spectrometry and purification techniques
  • Experience with RP-HPLC, SAX-HPLC, UPLC, and LC-MS
  • Familiarity with instrumentation from Agilent, Waters, and/or Thermo and associated software
  • Excellent written and verbal communication skills
  • Proven ability to work independently and as part of a collaborative team
This is a great opportunity for an analytical expert looking to make an immediate impact on late-stage drug development programs in a fast-paced, GMP-driven environment.


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About the Company

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Connexion Systems + Engineering