Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.
Universal Cells, an affiliate of Astellas located in Seattle, WA, is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells to produce cells that avoid rejection and can be used in allogeneic cell therapy treatments to treat all patients that need them.
OUR GOAL - ONE CELL FOR EVERYONE
NO IMMUNE SUPPRESSION. NO DONOR MATCHING. NO REJECTION.
We are a dynamic team of research and scientific professionals who are passionate about turning science and innovation into medical solutions. Through our diversity, scientific knowledge, professional rigor and focus on innovation, we are merging our technology with the Astellas drug development expertise to unlock cures to many therapies. Join our team of committed, enthusiastic professionals devoted to making the most effective, life-saving cell therapy products in the world.
Universal Cells (UCI) is announcing a Sr. Research Associate, Clinical Gene Editing opportunity at their facility in Seattle, WA.
Universal Cells carries out AAV-mediated gene-editing of pluripotent stem cells using non-GMP processes in a controlled manufacturing environment. The Clinical Gene Editing Senior Research Associate will work as part of a team evaluating, planning, and executing all aspects of gene-editing and engineering of pluripotent stem cells. This position will provide scientific guidance for the generation of Universal Donor Cells and may lead other members to ensure efficient operation and on-time delivery of edited pluripotent stem cells. This position will require versatility in following complex procedures, utilizes strong technical knowledge, understands administrative operations, and troubleshooting methods. Will assist with all laboratory operations and take on more responsibility to provide content for various documents and reports. Will execute protocols smoothly, guide standardization collaboratively, and summarize results independently.
Essential Job Responsibilities:
* Designs, coordinates, and executes AAV-mediated gene-editing of pluripotent stem cells in a controlled manufacturing environment.
* Performs data collection, analysis and interpretation for stem cell culture and gene-editing processes.
* Leads group meetings and regularly presents at cross-functional team meetings.
* Prepares, reviews and approves the work of others, including but not limited to, technical slide decks, reports, Standard Operating Procedures (SOPs) and production batch records.
* Serves as a technical resource for preparation of regulatory filings.
* Supports Process Development to establish and transfer manufacturing processes.
* Identifies challenges in manufacturing operations and supports Process Development in troubleshooting issues in a timely manner.
* Serves as a subject matter expert on experimental methods and production processes.
* Ensures smooth day-to-day operations of manufacturing lab and coordinates activities across all team projects.
* Performs other duties as assigned or special projects as needed.
* The SRA will have trained to complete competency, with full team integration within 6 months.
* The SRA is a key Technical Operations position ensuring technical execution, documentation and real-time communication of gene-editing production activities to facilitate advancement of clinical candidates.
* This position reports to Director of Process Development and Cell Editing.
* Operates on a shifted schedule that includes at least one weekend day.
* Assist with onboarding, training and guidance to new team members and to junior RAs.
* An MS with 2+ years or a BS with 5+ years of highly relevant experience in mammalian cell culture
* Experience with genome engineering.
* Strong organizational, time management and problem-solving skills with scientific attention to details.
* Ability to work independently and ability to effectively collaborate with other teams.
* Excellent communication and interpersonal skills.
* Excellent work planning, organization, and record keeping.
* Strong work ethic with a passion for working in a fast-paced, dynamic and diverse work environment.
* This role will be on a shifted schedule, either Tuesday to Saturday OR Sunday to Thursday.
* Experience with pluripotent stem cell culturing.
* Experience with gene editing of pluripotent stem cells.
* Experience working in a GMP environment.
* Experience in leading teams preferred.
* Medical, Dental and Vision Insurance
* Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
* 401(k) match and annual company contribution
* Company paid life insurance
* Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
* Long Term Incentive Plan for eligible positions
* Referral bonus program
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled
- Attention To Detail
- Cell Cultures
- Clinical Works
- Data Collection