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SRA - Antibody Engineering

Apex Systems South San Francisco Full-Time
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Primary responsibilities include, but are not limited to:

  • Characterize antibody binding and relate to functionality for candidate antibodies using FACS
  • Perform transient and stable transfection in different cell lines for routine recombinant protein production
  • Lead the generation of stable cell lines for the expression of proteins and monoclonal and bispecific antibodies
  • Lead the optimization of cell culture processes and help implement novel technologies
  • Maintain cell culture facilities and culture cell lines as required for experiments
  • Maintain accurate inventory of the produced proteins
  • Maintain electronic laboratory notebook
  • Analyze and interpret data, generate reports, communicate project updates as appropriate
  • Participate and present scientific data in team meetings


  • BS or MS in immunology, cell biology, molecular biology, protein/antibody engineering or closely related fields with 10+  years (BS), 5+  years (MS) or 2+  years (PhD) industry experience
  • Minimum of two (2)  years of experience with cytometry instrument platforms (analyzers, sorters).  Proficiency with cytometry data analysis software (eg BD FACS Diva software, FlowJo etc)
  • Expertise in cell culture and managing cell lines essential
  • Proficient in Mammalian cell culture and cell transfection methodologies
  • Ability to work independently, multi-task and meet deadlines in a fast-paced environment
  • Highly motivated, organized and disciplined record keeping
  • Excellent verbal and written communication skills
  • Proven ability to learn, adapt and develop in an evolving work environment
  • Committed to the values of integrity, scientific rigor and transparency
  • Strong desire to work in a dynamic start-up environment is essential
  • Current US work authorization required

EEO Employer

Apex is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at 844-463-6178


Recommended skills

Flow Jo
Cell Cultures
Molecular Biology
Recombinant Dna
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