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Scientist, BioScience at AstraZeneca PLC

Scientist, BioScience

AstraZeneca PLC Gaithersburg, MD (Onsite) Full-Time
Scientist, BioScience - Gaithersburg, MD

Do you have expertise in, and a passion for discovering & delivering life-changing medicines to patients? Would you like to apply your expertise in Biologics Engineering in a company that follows the science and turns ideas into life changing medicines? AstraZeneca might be the one for you!

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies.

At AZ, we're proud to have an exceptional workplace culture that encourages innovation and collaboration. Here, employees are empowered to express diverse perspectives - and made to feel valued, energized and rewarded for their ideas and creativity. AZ is a place where passionate people can immerse themselves in their work and make significant contributions to scientific excellence and medicines - does this describe a place where you would like to work?

We are seeking a candidate with passion for discovering and delivering life-changing medicines to patients. The successful applicant is expected to have good understanding of a range of procedures related to recombinant antibody identification through yeast display libraries. They will execute laboratory experiments, develop methods, generate, interpret, and report scientific data. They will work within an interactive team of experts to support COVID-19 therapeutics and also advance pipeline programs in various therapeutic areas.

What you'll do:

* Support discovery campaigns using phage or yeast display technologies for the identification and characterization of therapeutic antibodies.
* Use molecular biology skills to build and sort diverse display libraries, then amplify outputs by next-generation sequencing.
* Characterize isolated clones independently using transient transfection, protein purification and binding assays.
* Prepare, analyse, and present data internally and externally.
* Work within a matrixed environment across multiple groups

Education, Qualifications, Skills and Experience:

Essential Requirements:

o Bachelor's degree in in Molecular Biology, Biochemistry, Immunology or related disciplines with 5+ years of laboratory experience.

o Experience with bacterial and yeast culture, cell sorting and DNA characterization.

o Extensive and current hands-on experience in a wide-variety of Molecular Biology techniques, including cloning, DNA sequence analysis, protein expression and purification and tissue culture.

o Ability to work independently and in a team setting.

o Self-motivated, diligent, and flexible in accommodating shifting priorities.

o Strong communication and interpersonal skills, both oral and written, with supervisor, team, and various cross-functional project team members.

o Proficient in Microsoft Office tools including Outlook, Word, Excel, and Power Point, as well as flow cytometry analysis tools such as FlowJo.

o Maintain accurate and well-organized laboratory records, including worksheets, lab notebooks, inventories, and databases.

Preferred Requirements:

o Master's degree in a related field with 2+ years of relevant laboratory experience.

o Experience with discovery platforms including phage display.

o Experience with NGS experimental design, library construction and data analysis.

o Transfection/electroporation, culturing and expansion of mammalian cells.

o Background in cell biology is highly desired.

o Experience with ELISA, MSD and biolayer inferometry binding assays.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big! Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

Site Description

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, and nature walks. This is where you'll find newly designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams.

So, what's next?

A place built on courage, curiosity, and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take calculated risks that write the next chapter for our pipeline.

If you are swift to action, confident to lead, willing to collaborate, and passionate about the possibilities, then we are keen to hear from you!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn [ Link removed ] - Click here to apply to Scientist, BioScience />
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Next steps:

Apply today, or connect with our Talent Acquisition Partner - Kayla Harris: [ Link removed ] - Click here to apply to Scientist, BioScience for a confidential discussion to explore this opportunity further. We are looking forward to hearing from you!

Date Posted


Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

Recommended Skills

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