PhD Medicinal/Synthetic Organic Chemist

Description Business Unit:  NIBR

Country:  USA

Company/Legal Entity:  USA Novartis Institutes for BioMedical Research, Inc., Cambridge, MA

Posting Functional Area:  Global Discovery Chemistry

Employment Type:  Permanent

Major responsibilities will include the design, synthesis, purification and characterization of novel chemical entities. The qualified individual must be proficient in identifying structure activity relationships (SAR) to address lead optimization, potency, selectivity, pharmacokinetics and in vivo efficacy. The qualified individual is expected to contribute to pre-clinical research projects as a project team member. Additionally, the qualified individual will be expected to supervise the professional development and mentoring of junior-level scientific staff. The individual will collaborate / interact with a broad group of scientists within Novartis and with external collaborators. These scientists will include biologists, medicinal chemists, pharmacologists and a variety of personnel in Discovery Technology.

Requirements * Ph.D. in synthetic organic or medicinal chemistry * 2-6 years of relevant post doctoral or industrial experience * Experience managing BS/MS chemists * Proven track record of innovative project contributions including peer-reviewed publications * Ability to work independently and ability to interact with a multidisciplinary team of medicinal chemists, biologists, pharmacologists and external collaborators. * Experience with modern structure-based drug design and multi-parallel synthesis is a plus. * Excellent oral / written communication and presentation skills * Flexibility to work in a dynamic environment