Postdoctoral Fellow, DMPK

Description Business Unit:  NIBR

Country:  USA

Company/Legal Entity:  USA Novartis Pharmaceuticals Corporation, East Hanover, NJ

Posting Functional Area:  Translational Sciences

Employment Type:  Apprentice / InternshipIf temporary, length of contract3 years

This is an exciting opportunity to perform academic-oriented research in an industrial setting East Hanover, NJ. The postdoctoral fellow will be expected to submit an innovative research plan as part of the application process. This position will be responsible for interacting with project teams within our DMPK function to establish PK/PD models. Modeling using WinNonlin, NONMEM and/or other appropriate simulation tools e.g. GastroPlus is highly desired. The successful candidate will design, conduct and interpret PK and PK/PD studies to build preclinical and clinical PK/PD models for the projection of early efficacious human dosing regimen. Primary responsibilities also include the development and validation of PBPK and PBPK/PD models and development of modeling strategies. The candidate will routinely advise drug development teams on PK/PD related issues for oral and non-oral delivery routes. The work carried out by this individual is expected to lead to high quality publications in peer reviewed journals. Key features of these positions include high visibility within research at Novartis and opportunities to interact with senior scientific leadership individually and at annual forums.

Requirements Ph.D. degree with 0-3 years of post-PhD research experience in pharmacokinetics, biopharmaceutics, biomedical engineering, chemical engineering, or other related discipline with specific experience in PK/PD and/or PK modeling is required. The candidate must be able to work independently and have a strong understanding of PK/PD. The candidate should should be able to provide technical assistance on individual projects, spanning across multiple therapeutic areas. Hands-on experience in PK and PK/PD modeling is a must. Good oral and written communication skills are required. Previous experience with some of the PKPD softwares such as: WinNonlin; ADAPT; NONMEM, GastroPlus.